I recently found this distributing computer project which I have been running for a day now. While the client has only been available for a few days, it already seems quite well polished. The program is not limited to Windows, but also includes Solaris, Unix, and other platforms already. The program itself is working on simulating protein folding for the purpose of medical research, but it is taking a different approach to doing so then Folding@home. There is additional information about the project here with technical details on the methods that are being used with the project. This might be a project some anandtech forum members might want to give a try.