I think that's the key to all of this. You can add up all the possible power-draws of devices within the computer case, and assume the worst case has them all working full-bore simultaneously, but that will never happen.
You could spend a lot of time and trouble "measuring" an average "usage-profile" for yourself.
But the peak efficiency for good PSU's is somewhere around the median or -- as has been said -- 50% of the rated PSU output.
The other thing, and I said it elsewhere in these forums recently, the PSU is rated for its sustained, mean output. This would make arguments about graphics card power spikes less relevant for good PSUs, and more relevant for PSUs of questionable rated output. If an XFX rebranded Seasonic 750W unit is capable of sustaining output up to 950W, it tells you that quality PSUs are rated conservatively.
That's why I believe I can "stand pat" with a 650W Seasonic with two OC'd GTX 970's in SLI. Although I won't exceed the rated output, anyone who does would have lower efficiency than the lower level measured just below that output, but the decline is probably a continuum. Conversely, if you use a PSU rated at 850W or 1,000W, and your range of power-consumption within the PC is between 85W and 300W, the PSU will be operating at below rated/peak efficiency.
I like to say it's a "Goldi-Locks, Three-bears and porridge problem." Which PSU is "just right?" :biggrin: