*Obligatory Windows Home Server reply*
Stand alone software, however, I'd have to go with True Image. JUST MAKE SURE TO TEST YOUR RAM! I had years worth of backups that were bad because I was using bad RAM, and I had no idea until I tried to use the backup. Wouldn't pull any data from it. Kept getting a specific error, and after researching that error, I tested my RAM. I had to toss every backup I had (tested before I killed it of course).