There is no point in arguing against irrational beliefs people hold. You can't argue or counter beliefs that are based on completely irrational presumptions based out of delusion, emotion, fear etc. I think Hitchens, Dawkins and others like him who rally against religions and their teachings are doing something worthwhile, but it's the wrong way to go about it.
If a schizophrenic is in the room screaming about demons chasing them, you cannot reason them down from that position because as irrational as it is, they genuinely can see and hear the demon because of their brain being functionally broken. In their case you can give them medication to prevent their brain from creating hallucinations and stop the irrational behaviour. There is no medication to treat the delusion of religion, now you're dealing with programmed behaviour, fear of death, the ego etc.
The best medication for religion has been hard science, backed up by evidence, that disproves the stories of the Torah, Bible and Koran. The Earth is not 6000 years old - more like 6 billion, there was no garden of eden - the earth was a molten rock at inception, humans could not begin from just one single man and woman - the gene pool was too small, snakes don't talk -they lack the vocal chords and intelligence, the lights in the sky will not fall to the earth during the apocalypse - those lights are actually stars thousands, millions and billions of light years away etc. etc. etc.
All the science based claims of religions are being continually shut down. It's like has been said, god is an ever-receding pocket of ignorance. If we don't understand and haven't learned how a system works; 'oh that's god' Once we figure out that one, 'oh it's actually this system at work, here's how it works and here's how we can prove it' We still see the same broken logic at work today; science discovers evidence of the big bang, now the claim is 'oh god made the big bang happen, the creation story of the bible is no longer factual, it's all just metaphor' If you'd have been alive a thousand years ago and claimed that the creation story of the bible was not hard truth, you'd be executed, today that position is no longer tenable.
I don't think there needs to be an active vocal movement against religion, new knowledge is continually eroding the bubble of ignorance that is religion's attempt to explain the universe with wild stories of magical events. In just 2000 years we've nullified all the major scientific claims of religion, it's reasonable to expect in another 2000 that religion and all the ills and irrationality it spreads in society will be mostly a thing of the past.