In 2013, 743 people lost their lives in bicycle/motor vehicle crashes, just under two people every day of the year in the U.S. This is the highest number of fatalities since 2006, when 772 were killed, and a major incurease from from the 682 bicyclist fatalities reported in 2011. These numbers represent just over two percent of the total number of people killed and injured in traffic crashes in 2012.
The number of estimated bicyclist injuries dropped to 48,000 in 2013, down from 49,000 in 2012. Injuries have hovered around 50,000 in recent years with 52,000 injuries in 2008, 51,000 in 2009, and 52,000 again in 2010. However, these figures have not always been so steady. Injuries totaled 68,000 in 1993 and slowly fell to 41,000 in 2003, only to rise again. Like walking injury figures, research into hospital records shows that only a fraction of bicycle crashes causing injury are ever recorded by the police, possibly as low as ten percent.
Obviously with 743 deaths per year, there are risks associated with riding a bicycle. Bicycle fatalities represent less than two percent of all traffic fatalities, and yet bicycle trips account for only one percent of all trips in the United States. However, bicycling remains a healthful, inherently safe activity for tens of millions of people every year.
As mentioned, bicyclists seem to be over-represented in the crash data, but, there is no reliable source of exposure data as we don't know how many miles bicyclists travel each year, and we don't know how long it takes them to cover those miles (and thus how long they are exposed to motor vehicle traffic). Risk based on exposure varies by time of day (with night time being more risky), experience level of rider, location of riding, alcohol use, and many other factors. Until we have better exposure measures, we just don't know how bicyclist risk compares to other modes, but the health benefits of riding may offset some of this risk.