Financial Times Person of the Year

[ch33zw1z]

Coffee increases cholesterol??

Experts have directed me differently. Example, when I started getting bloodwork done, coffee was not allowed during the fast. Now they say it’s cool. My total cholesterol was always so high that a 20 point change was negligible. As I inched closer to 200, I was looking for ways to get lower, as a lifelong addict of something or another, coffee had been with me for 25 years and I wanted to prove I could quit. Lo and behold, next bloodwork was even better. I’ve had two done sans coffee, both under 200. It’s seriously a daily struggle tho to abstain, shout out to my wife who gets to hear my daily belly aching about it

While my 2023 goal was to quit all recreational drug usage, I didn’t cut caffeine completely, I still use 1-2 green tea bags a day. But…I’m off the 25 year coffee dependency

 

[hal2kilo]

Experts have directed me differently. Example, when I started getting bloodwork done, coffee was not allowed during the fast. Now they say it’s cool. My total cholesterol was always so high that a 20 point change was negligible. As I inched closer to 200, I was looking for ways to get lower, as a lifelong addict of something or another, coffee had been with me for 25 years and I wanted to prove I could quit. Lo and behold, next bloodwork was even better. I’ve had two done sans coffee, both under 200. It’s seriously a daily struggle tho to abstain, shout out to my wife who gets to hear my daily belly aching about it

While my 2023 goal was to quit all recreational drug usage, I didn’t cut caffeine completely, I still use 1-2 green tea bags a day. But…I’m off the 25 year coffee dependency

Sorry, I have to have at least one cup of coffee at day, mostly 2, very rarely 3. I think I will live. Fortunately, atorvastatin does the job quite well for me. Exercise takes care of the LDL's.

 

[ch33zw1z]

Sorry, I have to have at least one cup of coffee at day, mostly 2, very rarely 3. I think I will live. Fortunately, atorvastatin does the job quite well for me. Exercise takes care of the LDL's.

It’s so much about genetics it’s ridiculous

 

[repoman0]

Coffee increases inflammation, which encourages cholesterol plaque buildup in arteries. Note that cholesterol is naturally occurring in our bloodstream and isn't a problem; its the cholesterol sticking to arteries that's an issue.

Seems to highly depend on the individual. For many people studies seem to show that coffee reduces inflammation and risk of various diseases.

Coffee and Inflammation: Is There a Connection?

Coffee is a popular beverage that’s rich in antioxidants and other beneficial compounds. This article reviews coffee’s effects on inflammation, as well as whether decaffeinated coffee has the same effects.

www.healthline.com

9 Reasons Why (the Right Amount of) Coffee Is Good for You

A Johns Hopkins research nutritionist shares the benefits of coffee and a recipe for a healthy pumpkin spice latte smoothie.

www.hopkinsmedicine.org

Consumption of coffee or caffeine and serum concentration of inflammatory markers: A systematic review - PubMed

Coffee consumption is associated with reduced risk of conditions that share low-grade inflammation as their physiopathological basis. We therefore summarized the effects of coffee or coffee components on serum levels of inflammatory markers. Clinical trials assessing the effect of coffee...

pubmed.ncbi.nlm.nih.gov

 

[Denly]

Cut pop, cut coffee to 1 per day and no more 3x3 or 4x4, don't eat meat during daylight, if you drink switch it to wine instead of beer, mix up some fruits vegan protein drinks and walk anywhere within 1km(0.6 freedom unit) You will be back to size M by the end of the years and save yourself alot of money along the way.

 

[uallas5]

Cut pop, cut coffee to 1 per day and no more 3x3 or 4x4, don't eat meat during daylight, if you drink switch it to wine instead of beer, mix up some fruits vegan protein drinks and walk anywhere within 1km(0.6 freedom unit) You will be back to size M by the end of the years and save yourself alot of money along the way.

I assume you mean don't eat meat for lunch? Not eating during daylight is highly dependent on your location. When I lived in Scotland, daylight during the summer would start well before breakfast and end well after dinner. (We could go to a club and it would be twilight and when we'd leave the dawn would be about to break.)

 

[BurnItDwn]

I assume you mean don't eat meat for lunch? Not eating during daylight is highly dependent on your location. When I lived in Scotland, daylight during the summer would start well before breakfast and end well after dinner. (We could go to a club and it would be twilight and when we'd leave the dawn would be about to break.)

On top of that, Wine has a lot more sugar in it than healthy drinks like Scotch. (though dry wines are better than sweet wines in general).

 

[Denly]

I assume you mean don't eat meat for lunch? Not eating during daylight is highly dependent on your location. When I lived in Scotland, daylight during the summer would start well before breakfast and end well after dinner. (We could go to a club and it would be twilight and when we'd leave the dawn would be about to break.)

Yes I meant Breakfast and lunch, Cancuck here in my location sundown after 9pm in the summer I know what you meant. But when you put it this way it might not be a bad idea to be a vegan for half a year.

On top of that, Wine has a lot more sugar in it than healthy drinks like Scotch. (though dry wines are better than sweet wines in general).

Most wines contain under 5g of sugar/L and don't affect uric acid like beer, plus a bit of health benefit.

 

[BurnItDwn]

Most wines contain under 5g of sugar/L and don't affect uric acid like beer, plus a bit of health benefit.

Sorry i was somewhat joking by calling Scotch a "healthy" drink. I didn't intend rudeness against you.
I do agree that dry wines are quite reasonable when it comes to the carb levels, and I love my dry reds. (Lately been discovering a love for extra dry sherry as well.)
My wife on the other hand, loves her Moscato, which usually has well over 100gm of sugar in a 750ml bottle.

 

[Denly]

Sorry i was somewhat joking by calling Scotch a "healthy" drink. I didn't intend rudeness against you.
I do agree that dry wines are quite reasonable when it comes to the carb levels, and I love my dry reds. (Lately been discovering a love for extra dry sherry as well.)
My wife on the other hand, loves her Moscato, which usually has well over 100gm of sugar in a 750ml bottle.

None taken, not sure about how "healthy" Scotch or other whisky are but I do find that my body agrees with wine/whisky more than beer. Guess that's because beer doesn't leave me room to down a lot of water while I drink.

 

[biostud]

Up up an away!

Novo Nordisk hits $500 billion in market value as it flags soaring demand for Wegovy, Ozempic

Novo Nordisk, Europe's largest company by market capitalization, on Wednesday reported better-than-expected 2023 earnings.

www.cnbc.com

 

[nakedfrog]

Wow 😯
I only know of one person specifically, who is diabetic and has needed to lose weight for as long as I've known them, but just seems rooted in the idea that they can't change.

https://www.cnn.com/2024/05/10/health/ozempic-glp-1-survey-kff/index.html

 

[biostud]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

 

[nakedfrog]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

Fast food prices got too high, and semaglutide clinics are springing up in cities.

 

[iRONic]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

The only way that could've happened was they forgot to survey Kentucky!

 

[Dave_5k]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

"There are now more than 50 anti-obesity drugs in clinical development from about 40 companies, according to Bloomberg Intelligence. Many target GLP-1 and other hormones, including GIP, glucagon and amylin. Sales of the drugs, for both diabetes and obesity, exceeded $19 billion in 2023."

And these drugs actually work long term for nearly everyone, unlike diets or weight loss programs. Now that researchers are actually treating obesity as a disease and finding there are real treatments when they do so.

At a cost of around $1000 per 1 month supply in the U.S., $19 billion in sales means 1.6 million U.S. adults were on drugs that suppress appetite in 2023 (although that likely understates the figure, as the numbers were ramping rapidly during the year). These new drugs would support nearly a 1% decline in obesity rate for 2023, by themselves.

Of course, 99% of that ridiculous U.S. price is pure profit now, long since having fully recovered research costs, and being produced for, at most, $10 per monthly dose and likely less.

 

[alien42]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

Gotta be Ozempic.

 

[ch33zw1z]

https://twitter.com/x/status/1842163184838250764

Something has happened to obesity in the US.

Quick let’s review the death rate

 

[Dave_5k]

Quick let’s review the death rate

That actually is a material contributing factor... around 200k-500k early deaths each year due to obesity, depending on which researcher you believe and how old of a study you look at (20 years ago the problem wasn't nearly as large, no pun intended...)

 

[ch33zw1z]

That actually is a material contributing factor... around 200k-500k early deaths each year due to obesity, depending on which researcher you believe and how old of a study you look at (20 years ago the problem wasn't nearly as large, no pun intended...)

Yea, and if we change the threshold for obesity, like instead of x.x bmi, it’s higher then there will be less as well. I’m not up to speed with this area, so just thinking about how this number maybe encouraging but misleading at the same time

 

[BurnItDwn]

Im pretty close to getting off of that chart through years of eating less starch and sugar. I only take metformin, not using any of those fancy new drugs. Doc is pleased with A1C so continuing current path. Maybe in a couple of years, if I slowly drop some more weight, i'll be off of that chart.

 

[hal2kilo]

Right, and that's kind of my point. It's not just the way we eat in "modern society", but the way we have come to simply throw drugs at every perceived health problem instead of looking at better options.

If you don't buy the majority of your food on the periphery of the store, you are not doing it right in the first place. Processed foods are a killer. This country needs it, plus it's not really being lazy if it reduces your desire for the amount of food you eat. It seems to have other good side effects like reducing bad habits like drinking. I did not realize that these are formulations of FDA approved products and there are all kinds of non-big pharma outfits making similar formulations. Prices will do down also.

 

[manly]

Good news in Canada!

Novo Nordisk Loses Canadian Patent Protection For Blockbuster Diabetes Drug Over Unpaid $450 Fee - Slashdot

Pharmaceutical giant Novo Nordisk forfeited patent protection for semaglutide -- the active ingredient in blockbuster diabetes and weight loss drugs Ozempic and Wegovy -- in Canada after failing to pay a $450 maintenance fee in 2019. The company had paid maintenance fees through 2018 but...

science.slashdot.org

 

[sdifox]

I am losing weight without it I just can't eat as much as I used to xd.

BMI 25.8 is apparently overweight