So, if you really care about mem performance but you can't use high-end mems with taller heatsinks and add-on coolers but you have better latencies is that better? I dont think so. At least not for a high-end system.
I see your point, Blazer7, and the motherboard does have some issues with tight layout in certain circumstances. However, as you said, the ultimate solution is water cooling. It works GREAT.
To the OP:
I highly recommend the GA-X58A series mobos. I have a -UD3R and a -UD5. They have about every feature one could wish for. As has been posted many places, there are three primary issues with layout tightness that might drive you nuts:
1. The first PCIExpress-1 slot (PCIEX1_1) is jammed right up against the Intel X58A heatsink, and a number of PCIEx-1 cards won't fit in that slot. So, if you really want to use both PCIEx-1 slots, you'd best make sure your cards will fit before buying the motherboard.
2. As Blazer stated, the RAM DIMM slots are very close to the CPU, so if you want to put in a whopping big conventional cooler, and have fast RAM with tall heatsinks, you might be unhappy. If you want to do serious overclocking, and I agree with Blazer that often dictates RAM with tall 'sinks, you really need to go water cooled. Standard i7 series CPU coolers are just fine and plenty of clearance.
3. The SATA connectors are right angle and in even mid-tower cases, it can be a real pain to work with them. You need to match the case to this mobo with an eye to how the SATA connectors are going to work. As this mobo has the most SATA connectors on the market, I would assume others buy these boards as I did to stuff a lot of HDD in there, so the obvious choice is a roomy full tower with lots of drive bays.
I personally like the Cooler Master 690 II Advanced case with this mobo. With it, you can put the HDD's in with the connectors facing the right side of the case, and there conveniently are holes in the mobo support panel exactly where the mobo SATA connectors are so you can neatly and easily run the SATA cables around the back, through the holes, and easily plug into the connectors. This case rocks for a million other reasons too, but it just happens to fit the GA-X58A like a dream.
If you do get the motherboard, upgrade the BIOS immediately, and download the updated manual. The Rev 1.0 hardware printed manual I got with the mobo and the F1 BIOS didn't match up, and the RAID configuration information is badly wrong. It's probably worth waiting until the Rev 2.0 hardware is out, although there are deals on the UD5 rev 1.0 right now with them on sale plus a $20 rebate from Gigabyte (I assume to finish moving the stockpile of Rev 1.0 boards.) The rev 1.0 boards are fine, the rev 2.0 is just a little enhanced. It does, however, come with better BIOS and doco.