The beauty of those large fans is that they spin slow and are practically silent. If you have air cooled GPU's, the side fan helps to feed them with fresh air.
The only down-side: the case must be made for them or you must mod the case. they only come in the 3-pin flavor -- although some would see that as a positive factor over choice and options.
I doubt that these fans have the longevity of smaller units; I can only say that my NZXT 0.70A unit failed after 30 months. But even for its 166 CFM airflow, that fan doesn't get rave customer reviews.
Just digressing -- noticed something else recently, with my replacement NZXT. Background: you have to mod or innovate using the fan other than NZXT cases -- either drilling four holes for rivets (or [ugh] screws.
I wrapped the feet of the fan in Spire foam rubber strips and used black wire ties wrapped around the rubber to secure the fan. I used foam-art-board cutouts -- cut to the fan shape -- to block off vent-holes that fan can't use. I sealed any leak points with more strips of Spire.
Took the side-panel off the other day to look at something while the computer and fan were running. Amazing! There is a motor-whine or whirring that comes directly from the fan motor. Apparently my mounting and "insulating" eliminates that noise entirely: it can't be heard from the case exterior.