who's gotten their 2nd booster?

Page 2 - Seeking answers? Join the AnandTech community: where nearly half-a-million members share solutions and discuss the latest tech.

dullard

Elite Member
May 21, 2001
25,764
4,289
126
mRNA was invented/discovered in 1987.

Next up?
Neither is correct. mRNA is in every cell of every living being (it is in every single organic thing you eat). It was "invented" with the first lifeform. It was discovered in the 1960s. Now, nothing much was really done with mRNA until the 1980s though.

But, I'm not trying to get to anyone. I'm really curious as to why people are still opposed to the vaccines and how their beliefs change over time (or are set in stone).
 

Charmonium

Lifer
May 15, 2015
10,321
3,406
136
The m in mRNA just stands for messenger. I'm not a molecular biologist so this may not be completely accurate. But when the nucleus needs to send commands out to the cytoplasm of the cell, where all of the actual work gets done, it does via mRNA.

mRNA has been a target of tons of research. Not so much for its ability to fake being a virus, but because many systems in your cells function on what you might call a knife's edge. You have some mRNA that up-regulates certain processes and others that down-regulate that same process.

So what does that mean. I can't think of a real example (way over my paygrade) but let's say you have two strands of mRNA - one that tends to increase the amount of say dopamine that a neuron produces and one that tends to decrease its production. Think of it like those tweeters that have wires suspended between two magnetic plates. What makes them work? Well, the voltage of course. The ribbons are exquisitely tuned that just a very nominal change in voltage can make them move. That's why they so prized by audiophiles for so long.

So what tips the balance between battling mRNAs. Who the f* knows (not me). But you can see the value of such a precise and sensitive system.
 

nakedfrog

No Lifer
Apr 3, 2001
61,132
16,586
136
People with a miniature computer/digital camera in their hand will talk about how mRNA vaccines are "too new" and/or "developed too quickly".
 

Charmonium

Lifer
May 15, 2015
10,321
3,406
136
People with a miniature computer/digital camera in their hand will talk about how mRNA vaccines are "too new" and/or "developed too quickly".
Can't they just get the J&J vaccine. IDK if it works on the current variants but IIRC, that's NOT an mRNA vax

edit: I mean f* me, it's gotta be better than nothing.

I think I'll go into that cat house with just my lambskin.
You know that not impermeable, right?
Eh, better than nothing.
 
Reactions: Captante

Brovane

Diamond Member
Dec 18, 2001
6,060
2,346
136
Neither is correct. mRNA is in every cell of every living being (it is in every single organic thing you eat). It was "invented" with the first lifeform. It was discovered in the 1960s. Now, nothing much was really done with mRNA until the 1980s though.

But, I'm not trying to get to anyone. I'm really curious as to why people are still opposed to the vaccines and how their beliefs change over time (or are set in stone).

I personally am vaccinated and have gotten the booster(team Pfizer) and so has my wife as well as our two teenage daughters. We had COVID in November/December of 2020 but still got vaccinated. However we made that decision because we are older and have co-morbidities. Our daughters wanted to get vaccinated so when eligible we got them vaccinated. They were both old enough to make that decision.

As far as vaccine hesitancy. IMHO there is a certain level of gas-lighting in my opinion for the vaccines from the government. There is some nuances going on that doesn't fit in the one size fits all the US government is trying to do for vaccine policy.

For example does it make sense for a 60-year old to get vaccinated and get boosted, absolutely. We now there is a significant reduction in the chance of hospitalization and mortality.
However for a health 25-year old who had a confirmed case of COVID and cleared the virus. What is the reduction in the chance of hospitalization and death for them by getting two shots of the Pfizer or Moderna vaccine? Maybe they don't need both shots. Maybe just one shot is good enough. I know there is claims that we don't know how long natural immunity from a infection lasts but we don't know how long vaccine induced immunity lasts either.

We know that with either vaccine induced immunity or immunity through a infection, it doesn't provide sterilizing immunity that some other vaccines or natural infection provides. There is plenty of examples of people having breakthrough cases after vaccination or a previous infection. I am very much pro-vaccine but against the vaccine mandates. My opinion would be different if we had a vaccine that produced sterilizing immunity against infection (Like the Measles vaccine or Polio Vaccine) but we are dealing with a Coronavirus that has significant animal reserves. Which means we are never going to eliminate it in the wild.
 
Reactions: Red Squirrel

Torn Mind

Lifer
Nov 25, 2012
12,004
2,748
136
I personally am vaccinated and have gotten the booster(team Pfizer) and so has my wife as well as our two teenage daughters. We had COVID in November/December of 2020 but still got vaccinated. However we made that decision because we are older and have co-morbidities. Our daughters wanted to get vaccinated so when eligible we got them vaccinated. They were both old enough to make that decision.

As far as vaccine hesitancy. IMHO there is a certain level of gas-lighting in my opinion for the vaccines from the government. There is some nuances going on that doesn't fit in the one size fits all the US government is trying to do for vaccine policy.

For example does it make sense for a 60-year old to get vaccinated and get boosted, absolutely. We now there is a significant reduction in the chance of hospitalization and mortality.
However for a health 25-year old who had a confirmed case of COVID and cleared the virus. What is the reduction in the chance of hospitalization and death for them by getting two shots of the Pfizer or Moderna vaccine? Maybe they don't need both shots. Maybe just one shot is good enough. I know there is claims that we don't know how long natural immunity from a infection lasts but we don't know how long vaccine induced immunity lasts either.

We know that with either vaccine induced immunity or immunity through a infection, it doesn't provide sterilizing immunity that some other vaccines or natural infection provides. There is plenty of examples of people having breakthrough cases after vaccination or a previous infection. I am very much pro-vaccine but against the vaccine mandates. My opinion would be different if we had a vaccine that produced sterilizing immunity against infection (Like the Measles vaccine or Polio Vaccine) but we are dealing with a Coronavirus that has significant animal reserves. Which means we are never going to eliminate it in the wild.
One legitimate reason for hesitancy is the belief that if one does draw the rare hand and has to deal with it, the "authorities" will not bother to provide care and run the proper battery of tests. Rather, they, as if operating unconsciously in a hive mind, will fudge and gaslight the patient so that the cause of their newfound maladies is anything but the vaccine.

The exploitation of diagnostic ambiguity is much like a mechanic pointing out a noise being made when the brakes are applied. A minor squeal due to lack of grease on the pads is not functionally relevant. It is an opportunity to make money because the owner might be persuaded that is an issue by the expert.

Likewise, the denial of diagnosing a complication of vaccine reaction as something else is not sensible is to keep the unfortunate quiet; generally, working in good faith to heal is better at purchasing silence than denial. But the medical industries loving keeping a buck, so they don't do more. This saves the insurance companies money and underreports incident so the science masters can have a better case due to said systemic underreporting. Or perhaps in some cases, a combination of stupidity and hubris, in which someone suffering from effects are deemed as vaccine deniers when they willingly took in a shot, maybe 2. One method is simply diagnose the effects as "anxiety", something endometriosis sufferers would also understand as well.

Medical pros are people who do a job, not a fucking trained Mother Teresa. Money matters a lot, often it is the first priority.

Data has also come out suggesting the J&J may have a better durability than the mRNA vaccines.
 
Reactions: Brovane

Captante

Lifer
Oct 20, 2003
30,337
10,854
136
Oops. That was intended to say that I'm not trying to trick or otherwise attack olds. I truly want to hear people's opinions.

Same here.

And after all those years in the basement Olds should be able to handle a little friendly abuse!

 

Brovane

Diamond Member
Dec 18, 2001
6,060
2,346
136
One legitimate reason for hesitancy is the belief that if one does draw the rare hand and has to deal with it, the "authorities" will not bother to provide care and run the proper battery of tests. Rather, they, as if operating unconsciously in a hive mind, will fudge and gaslight the patient so that the cause of their newfound maladies is anything but the vaccine.

The COVID-19 vaccines are still under the CICP (Countermeasure Injury Compensation Program) for manufacturers liability. With the CICP program an injured consumer from the vaccine has very limited recourse in getting compensated. There is no due progress, not provided legal counsel and a person can't be compensate for pain and suffering. We know with the vaccines the risk is not zero despite all the testing that has been done and some people unfortunately have been injured from the COVID-19 vaccines. Very unfortunately the J&J vaccine has been directly linked to some deaths. The COVID-19 vaccines should be moved from the CICP to the NVICP (National Vaccine Injury Compensation Program) so the people that are injured can get proper compensation for those injuries. With the push to make these vaccines mandatory we need to have a way to hold Big Pharma accountable for those that are injured. I believe that Companies need to be accountable for their products and compensation needs to be given to those injured from their products.
 

biostud

Lifer
Feb 27, 2003
19,461
6,516
136
Our center for health organization has said they actually misinformed about why we should be vaccinated in the start of the pandemic, and later changed their recommendations.
 
Reactions: Captante

MrSquished

Lifer
Jan 14, 2013
25,873
24,206
136
Waiting on my 2nd booster to see if there are any soon to come developments in variants or an updated booster.
 
Reactions: Brovane

Captante

Lifer
Oct 20, 2003
30,337
10,854
136
Our center for health organization has said they actually misinformed about why we should be vaccinated in the start of the pandemic, and later changed their recommendations.


Nothing like just admitting it when you screw up .... really helps making one appear credible to the public. (could teach the CDC a thing or two!)
 

Torn Mind

Lifer
Nov 25, 2012
12,004
2,748
136
The COVID-19 vaccines are still under the CICP (Countermeasure Injury Compensation Program) for manufacturers liability. With the CICP program an injured consumer from the vaccine has very limited recourse in getting compensated. There is no due progress, not provided legal counsel and a person can't be compensate for pain and suffering. We know with the vaccines the risk is not zero despite all the testing that has been done and some people unfortunately have been injured from the COVID-19 vaccines. Very unfortunately the J&J vaccine has been directly linked to some deaths. The COVID-19 vaccines should be moved from the CICP to the NVICP (National Vaccine Injury Compensation Program) so the people that are injured can get proper compensation for those injuries. With the push to make these vaccines mandatory we need to have a way to hold Big Pharma accountable for those that are injured. I believe that Companies need to be accountable for their products and compensation needs to be given to those injured from their products.
With the extension of the period from 4-8 weeks between dose 1 and dose 2 for younger men, it seems the "science" has somewhat recognized the myo- and pericarditis risk. The studies seem to indicate that the probabilities of issues might fall into the chances of drawing a poker hand like a straight flush, royal flush, or a four-of-a-kind. However, with the systemic under-reporting due to medical practitioners misdiagnosing and some people not knowing or completely unable to report to VAERS(the dead cannot report), that is a substantial concession.



Reading the above regarding the CICP, the above link points out one necessary component of winning is having a medical practitioner onboard stating the vax directly caused the issue. Also, the link is to a law firm, thus, this isn't some looney laymen just mouthing off. That's a loss by default if the person's doc determines it isn't because of the vaccine. Even if the doc is on board, the other docs on the "other side" have to be persuaded.

The second and more likely pathway is that a Claimant presents such specific, medical evidence that it convinces the agency that the Claimant’s health condition “is the direct result of the administration or use of a” covered vaccine. At minimum, a Claimant will probably have to have treating doctors provide specific, written opinions that the vaccine itself directly caused a diagnosed injury and resulting loss of work, and explain why. And that in itself will not satisfy the agency. Its own published guidance warns: “Such proof must be based on compelling, reliable, valid, medical and scientific evidence.” This standard of proof is much higher than the evidence of causation we must prove in court, which is typically preponderance of the evidence, or greater than 50% likelihood. Basically, the agency hires medical practitioners whose main qualification is to be highly skeptical of any claim that a vaccine results in injury, and unless your evidence is based upon well-established and undeniable consensus in the medical community, they can say no.
 

pmv

Lifer
May 30, 2008
14,597
9,461
136
Gotten what I'm fairly sure was my second booster. Only thing is I've lost track at this point of how many shots I've had. It might have been a third booster. Either way they sent me a letter saying I was eligible for another booster and, after procrastinating for a couple of weeks, got it done. Lord, I hope this is the end of it...but I suspect it may become a regular yearly thing from now on.
 

lxskllr

No Lifer
Nov 30, 2004
59,094
9,524
126
Pretty sure I just got a naturally induced booster. First home test came back negative, but I'm saving the other test for some time in the future. I'm certain what I've had wasn't a cold.
 

dank69

Lifer
Oct 6, 2009
36,925
32,096
136
Got my second booster a few weeks ago. 4x Pfizer now. No side effects this time, not even a sore arm.
 

Pohemi

Lifer
Oct 2, 2004
10,696
16,399
146
Had my 2nd booster (4th shot) back in August. Haven't had the new fangled variety yet.
 

nakedfrog

No Lifer
Apr 3, 2001
61,132
16,586
136
Handy, you can change your vote in the poll, so now that I've had it, I updated my vote. Got my Moderna bivalent booster 3 weeks ago today.
 
sale-70-410-exam    | Exam-200-125-pdf    | we-sale-70-410-exam    | hot-sale-70-410-exam    | Latest-exam-700-603-Dumps    | Dumps-98-363-exams-date    | Certs-200-125-date    | Dumps-300-075-exams-date    | hot-sale-book-C8010-726-book    | Hot-Sale-200-310-Exam    | Exam-Description-200-310-dumps?    | hot-sale-book-200-125-book    | Latest-Updated-300-209-Exam    | Dumps-210-260-exams-date    | Download-200-125-Exam-PDF    | Exam-Description-300-101-dumps    | Certs-300-101-date    | Hot-Sale-300-075-Exam    | Latest-exam-200-125-Dumps    | Exam-Description-200-125-dumps    | Latest-Updated-300-075-Exam    | hot-sale-book-210-260-book    | Dumps-200-901-exams-date    | Certs-200-901-date    | Latest-exam-1Z0-062-Dumps    | Hot-Sale-1Z0-062-Exam    | Certs-CSSLP-date    | 100%-Pass-70-383-Exams    | Latest-JN0-360-real-exam-questions    | 100%-Pass-4A0-100-Real-Exam-Questions    | Dumps-300-135-exams-date    | Passed-200-105-Tech-Exams    | Latest-Updated-200-310-Exam    | Download-300-070-Exam-PDF    | Hot-Sale-JN0-360-Exam    | 100%-Pass-JN0-360-Exams    | 100%-Pass-JN0-360-Real-Exam-Questions    | Dumps-JN0-360-exams-date    | Exam-Description-1Z0-876-dumps    | Latest-exam-1Z0-876-Dumps    | Dumps-HPE0-Y53-exams-date    | 2017-Latest-HPE0-Y53-Exam    | 100%-Pass-HPE0-Y53-Real-Exam-Questions    | Pass-4A0-100-Exam    | Latest-4A0-100-Questions    | Dumps-98-365-exams-date    | 2017-Latest-98-365-Exam    | 100%-Pass-VCS-254-Exams    | 2017-Latest-VCS-273-Exam    | Dumps-200-355-exams-date    | 2017-Latest-300-320-Exam    | Pass-300-101-Exam    | 100%-Pass-300-115-Exams    |
http://www.portvapes.co.uk/    | http://www.portvapes.co.uk/    |