Well, 10gbps is only 125MB/s which is far less than even a basic SSD. If it's local system use then the sky is the limit but, if it's network based then it leads to a cascade of upgrades.
The OS running the drive shouldn't matter. I use the same M2 based drives in both Linux / Windows though. The system for the U drives though is running Linux and is a full sized PC vs the laptop I use Windows on.
AFAIK none of the consumer NAS boxes will even have the proper connector to insert a U drive inside of them w/o swapping some hardware or paying through the nose for a top tier "NAS" off the shelf. The lack of airflow in a "NAS" though would be my first red flag before venturing into anything NVME based SSDs. SATA though on the other hand would be fine as they don't get as hot.
Code:
SMART/Health Information (NVMe Log 0x02)
Critical Warning: 0x00
Temperature: 40 Celsius
As for use I leave it powered on 24/7 like a NAS because the PC is my router for the network and performs a few other functions. I've rebuilt it a few times since I started with it back in 2015. With the box handling everything it's quickly evident when there's a storage issue and things stop working in other areas. The Micron drives though were a bit odd in how they "fail". Things looked fine until I went to write new data to them after some period of time. Things became unusable after a reboot and thus no data existing after that point. On the 2nd one I noticed I/O errors when troubleshooting issues with it. I tried to dig into it knowing I didn't stand a chance post reboot of figuring out the cause. I dug through tons of different resources and attempted to get the drive operational again before giving up on yet another drive in such a short period of time.
The odd thing about it though is they would still show up in system outputs. However, couldn't be seen in fdisk or any disk utility.
If they're NEW then hammer them a bit while you're in the return period so you don't get into a drawn out RMA situation. RMA's always seem to take longer than a swap through a retailer and you end up with a refurb in the end. With what these thing cost though that's not a good place to be in at full price.